Year : 2013 | Volume
: 12 | Issue : 3 | Page : 182--184
Familial trend in polycystic ovarian syndrome: Report of two cases
NN Joe-kechebelu1, SU Mbamara2, JI Ikechebelu4
1 Department of Community Medicine, Anambra State University, Awka; Fertility Unit of Life Specialist Hospital, Nnewi, Nigeria
2 Department of Obstetrics/Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria
Polycystic ovarian syndrome (PCOS) is an endocrine disorder with a strong genetic component. The affected females present with anovulatory cycles, a spectrum of menstrual disorders, and features of androgen excess.
We present the case of two sisters who were diagnosed with PCOS and have a family history of oligomenorrhoea in their grandmother and PCOS in their mother and sisters. They also have a family history of hypertension, diabetes mellitus, and breast mass which are known co-morbidities associated with PCOS. Both were managed successfully with ovulation induction using clomiphene citrate. PCOS could be familial as in our patients and further research is required to define the exact genetic pattern of inheritance.
J I Ikechebelu
Fertility Unit of Life Specialist Hospital, P.O.Box 244, Nnewi, Anambra State
|How to cite this article:|
Joe-kechebelu N N, Mbamara S U, Ikechebelu J I. Familial trend in polycystic ovarian syndrome: Report of two cases.Ann Afr Med 2013;12:182-184
|How to cite this URL:|
Joe-kechebelu N N, Mbamara S U, Ikechebelu J I. Familial trend in polycystic ovarian syndrome: Report of two cases. Ann Afr Med [serial online] 2013 [cited 2021 Jun 22 ];12:182-184
Available from: https://www.annalsafrmed.org/article.asp?issn=1596-3519;year=2013;volume=12;issue=3;spage=182;epage=184;aulast=Joe-kechebelu;type=0