| ORIGINAL ARTICLE |
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| Year : 2023 | Volume
: 22
| Issue : 2 | Page : 160-166 |
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Original research gender differences in recovering from cardiac and vascular surgery associated acute kidney injury: A six-year retrospective comparative study in Nigeria
Peter Kehinde Uduagbamen1, Michael Sanusi2, Olumide Baz Udom2
1 Division of Nephrology and Hypertension, Department of Internal Medicine, Bowen University/Bowen University Teaching Hospital, Ogbomosho; Division of Nephrology and Hypertension, Department of Internal Medicine, Ben Carson (Snr) School of Medicine, Babcock University/ Babcock University Teaching Hospital, Ilishan-Remo, Nigeria
2 Tristate Heart and Vascular Centre, Ben Carson (Snr) School of Medicine Babcock University/Babcock University Teaching Hospital, Ilishan-Remo, Nigeria
Correspondence Address:
Peter Kehinde Uduagbamen
Division of Nephrology and Hypertension, Department of Internal Medicine, Bowen University/Bowen University Teaching Hospital, Ogbomosho
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/aam.aam_81_21
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Introduction: Gender differences exist in the demographic, clinical characteristic and outcome of patients with cardiac and vascular surgery (CVS) associated acute kidney injury (AKI). Materials and Methods: This retrospective study had a total of 88 participants for which socio-demographic, clinical and laboratory (serum electrolyte, full blood count, urine analysis and urine volume, creatinine, and glomerular filtration rate) data of participants were taken preoperative and postoperative days 1, 7, and 30. Results: A total of 88 (66 males and 22 females) participants were studied. Diseases of the heart valves were more common in females than males. The mean age of the participants was 65.9 ± 6.9 years, with males 65.1 ± 7.6 years and females 68.3 ± 8.4 years, P = 0.02. Before surgery, a significantly greater proportion of females had kidney dysfunction compared to males, P = 0.003. Valvular surgery and coronary bypass were the most common surgeries. The proportion of emergency surgeries and admissions <7 days were significantly higher in females than males, P = 0.04 and P = 0.02, respectively. Full recovering from AKI was significantly higher in males as partial recovery and death were significantly lower in them, P = 0.02. Of the 35 (39.8%) who had dialysis, 85.7% recovered fully, 5.7% became dialysis, and dependent while 8.6% died. The predictors of nonrecovery from CVS-AKI were female gender, elderly, preoperative kidney dysfunction and AKI stage 3. Conclusion: Males with AKI were younger than the females. Valvular surgeries were most common. Background kidney dysfunction and advance age were risk factors for AKI. Postoperative, AKI was commoner in males who were more likely to recover full kidney function. Optimizing patient preparation could reduce the incidence of CVS-AKI.
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