Annals of African Medicine
Home About AAM Editorial board Ahead of print Current Issue Archives Instructions Subscribe Contact us Search Login 
Year : 2013  |  Volume : 12  |  Issue : 3  |  Page : 182-184

Familial trend in polycystic ovarian syndrome: Report of two cases

1 Department of Community Medicine, Anambra State University, Awka; Fertility Unit of Life Specialist Hospital, Nnewi, Nigeria
2 Department of Obstetrics/Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria
3 Fertility Unit of Life Specialist Hospital, Nnewi, Nigeria

Correspondence Address:
J I Ikechebelu
Fertility Unit of Life Specialist Hospital, P.O.Box 244, Nnewi, Anambra State
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1596-3519.117630

Rights and Permissions

Polycystic ovarian syndrome (PCOS) is an endocrine disorder with a strong genetic component. The affected females present with anovulatory cycles, a spectrum of menstrual disorders, and features of androgen excess. We present the case of two sisters who were diagnosed with PCOS and have a family history of oligomenorrhoea in their grandmother and PCOS in their mother and sisters. They also have a family history of hypertension, diabetes mellitus, and breast mass which are known co-morbidities associated with PCOS. Both were managed successfully with ovulation induction using clomiphene citrate. PCOS could be familial as in our patients and further research is required to define the exact genetic pattern of inheritance.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded20    
    Comments [Add]    
    Cited by others 2    

Recommend this journal