Annals of African Medicine

ORIGINAL ARTICLE
Year
: 2018  |  Volume : 17  |  Issue : 3  |  Page : 151--155

Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria


Usman Mijinyawa Abubakar1, Abdu Lawan2, Isyaku Muhammad3 
1 Department of Ophthalmology, Murtala Muhammad Specialist Hospital, Kano, Nigeria
2 Department of Ophthalmology, Faculty of Clinical Sciences, College of Clinical Sciences, Bayero University, Kano, Nigeria
3 Department of Ophthalmology, Aminu Kano Teaching Hospital, Kano, Nigeria

Correspondence Address:
Dr. Usman Mijinyawa Abubakar
Department of Ophthalmology, Murtala Muhammad Specialist Hospital, Kano
Nigeria

Purpose: The purpose of this study is to determine predisposing factors, common bacterial causes, and antibiotic sensitivity of corneal ulcers in Murtala Muhammad Specialist Hospital. Materials and Methods: A prospective, cross-sectional, observational study was carried out on patients with corneal ulcers. Information on relevant clinical, sociodemographic profile was obtained. Examination includes visual acuity test and slit-lamp biomicroscopy, especially fluorescein staining. Corneal scrapings from the ulcer were inoculated onto the selected solid culture media plates. Gram staining for microscopic examination was done. Antibiotic sensitivity test on different antibiograms was done using modified Kirby–Bauer technique, determining bacterial isolate sensitivity or resistance to relevant antibiotics (chloramphenicol, ciprofloxacin, ofloxacin, gentamicin, tetracycline, ceftazidime, ceftriaxone, cefotaxime, and penicillin). Results: A total of 77 patients with corneal ulcer were examined. Ocular trauma, application of harmful traditional eye medication, and use of unspecified topical medication before presentation were among the predisposing factors. Bacterial growth was seen in 46.8% of the samples, of which 28.6% of the growth were Gram-positive. The common bacteria isolated were Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, Proteus species, and Klebsiella pneumoniae. Isolates were sensitive to ciprofloxacin and ofloxacin while an intermediate sensitivity was seen with chloramphenicol and gentamicin. Isolates were resistant to tetracycline, ceftazidime, ceftriaxone, cefotaxime, and penicillin. Conclusion: Ocular trauma was the major predisposing factor to corneal ulcer, and Staphylococcus species was the major bacterial organism isolated. Isolates were found to be sensitive to ciprofloxacin and ofloxacin, while an intermediate sensitivity was seen with chloramphenicol and gentamicin.


How to cite this article:
Abubakar UM, Lawan A, Muhammad I. Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria.Ann Afr Med 2018;17:151-155


How to cite this URL:
Abubakar UM, Lawan A, Muhammad I. Clinical pattern and antibiotic sensitivity of bacterial corneal ulcers in Kano, Northern Nigeria. Ann Afr Med [serial online] 2018 [cited 2019 Aug 25 ];17:151-155
Available from: http://www.annalsafrmed.org/article.asp?issn=1596-3519;year=2018;volume=17;issue=3;spage=151;epage=155;aulast=Abubakar;type=0