Annals of African Medicine
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CASE REPORT
Year : 2020  |  Volume : 19  |  Issue : 2  |  Page : 150-152

Eruptive neurofibromas in pregnancy


Dermatology Unit, Department of Medicine, Barau Dikko Teaching Hospital, Kaduna State University, Kaduna, Nigeria

Correspondence Address:
Dr. Husain Yahya
Dermatology Unit, Department of Medicine, Barau Dikko Teaching Hospital, PO Box 9727, Kaduna
Nigeria
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aam.aam_37_19

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Neurofibromatosis type 1 is the most common inherited nervous system disorder affecting 1 in 3500 live births. Cutaneous neurofibromas, the most characteristic feature of the disease, begin to appear in adolescence and continue throughout adulthood. Although neurofibromas have been noted to increase in size or number during pregnancy, there have been very few reports of eruption of a large number of lesions during this period. We report a case of a 24-year-old Nigerian woman of 32-week gestation who presented with a history of sudden eruption of neurofibromas during the current pregnancy and the previous one 3 years earlier. We discuss how hormones and growth factors contribute to the increase in numbers of neurofibromas during pregnancy, which is occasionally severe, as in our case, and the complications which may arise in the mother and fetus.


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