Annals of African Medicine
Home About AAM Editorial board Ahead of print Current Issue Archives Instructions Subscribe Contact us Search Login 
ORIGINAL ARTICLE
Year : 2015  |  Volume : 14  |  Issue : 1  |  Page : 57-61

Is prostate-specific antigen a reliable marker for uterine leiomyoma detection?


Department of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Alireza Abdollahi
Keshavarz Blvd, Imam Hospitals Complex, Tehran
Iran
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1596-3519.148743

Rights and Permissions

Background: Now it is accepted that prostate-specific antigen (PSA) is expressed extra prostatically and it is clear that many hormonally regulated female tissues show detectable PSA levels. This study was conducted due to differences of view between researchers about the role of PSA in some women diseases. This study was designed to evaluate the clinical implication of serum PSA measurement in diagnosis or management of patients with uterine myoma. Materials and Methods: This was a case-control study. A total of 224 patients included in this study. Serum specimens were isolated and were stored at -70΀C until all specimens were completed. Wilcoxon's rank-sum test was used to identify statistically significant differences between the total PSA and free PSA measurements in patient groups. Results: We noticed that there is no statistical significant correlation between total or free serum PSA level of cases with uterine myoma and control group (P = 0.433 and 0.700, respectively). Furthermore, no statistical difference was considered either in size or frequency of leiomyomas and free or total serum PSA (P = 0.126 and 0.433 and P = 0.997 and 0.442, respectively). Conclusion: We concluded that serum PSA measurement has little clinical utility in diagnosis or management of uterine leiomyoma.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1622    
    Printed60    
    Emailed1    
    PDF Downloaded3    
    Comments [Add]    

Recommend this journal